HELLP综合征7例临床分析

Clinical Analysis of Seven Cases with Hemolysis,Elevated Liver Enzymes and Low Platelets Syndrome.

目的分析7例HELLP综合征的临床特点,探讨该病的诊治。方法对7例HELLP综合征进行回顾性分析,其中完全性HELLP3例,部分性HELLP4例,比较两组的实验室指标、临床症状、分娩方式与孕产妇、围生儿结局。结果7例HELLP综合征患者均伴有不同程度的妊高征表现,完全性HELLP组总胆红素明显高于部分性HELLP组(P<0.05),其余各项实验室数据两组相比差异无统计学意义(P>0.05)。7例HELLP中1例死胎先予利凡诺引产,引产失败予剖宫取胎;6例HELLP采用剖宫产终止妊娠,均为早产,3例胎盘早剥,2例产后出血,终止妊娠的平均天数214.7±11.4天,新生儿重度窒息5例。结论HELLP综合征是一种严重的产科并发症,一旦诊断,终止妊娠是治疗最有效的措施。

Objective To investigate the diagnosis and treatment of HELLP syndrome through analyzing the clinical data of seven patients of HELLP syndrome. Methods We reviewed the study. There were three patients in the absolute HELLP group, four patients in the partial HELLP group. The laboratory data, clinical symptom, delivery method and the outcome of the pregnant women and infants of the two groups were analyzed. Results All the seven patients had clinical presentations of PIH. Total bilirubin（TB） value in absolute HELLP group was significantly higher than that in partial HELLP group（ P 〈 0. 05 ）. The other blood tests were not found significant difference between the two groups. All cases were delivered by cesarean section, including of one dead fetus and six immature labors. The average days of gestational age at delivery is 214.7 ±11.4 and there were three placental abruption, two postpartum hemorrhage and five severe asphyxia in newborn. Conclusion HELLP syndrome is a serious obstetric complication. Delivery is the most effective treatment.