采用微孔聚丙烯纤维材料的“四川联大Ⅰ型”管外流式(ELF)中空纤维膜式氧合器的研制

Design and Laboratory Manufacture of "SUU ** Type Ⅰ" Extra Luminal Flow Hollow Fibre Membrane Oxy genator with Microporous Polypropylene

介绍了“四川联大Ⅰ型”（以下简称：ＳＵＵⅠ）管外流式（ＥＬＦ）中空纤维膜式氧合器的研制、设计、外形制做及离心封端等过程，重点介绍了中空纤维膜材料选择，膜肺离心封端的原理、材料、设备及方法，并对聚氨酯胶进行离心封端的具体步聚作了较详细的叙述。作者根据自身在国外与国内的研制经验，认为离心封端的关键在于：（１）中空纤维膜材料的质量及成束质量；（２）聚氨酯封端胶材料固化特性的掌握及料量计算；（３）反应温度控制；（４）气体排除；（５）转速的控制；（６）纤维束的安装；（７）脱模和切头的时间掌握等方面。作者用外购的材料和自己设计制造的离心封端机成功地制造了我国第一个管外流式（ＥＬＦ）中空纤维成人氧合器。ＳＵＵⅠ膜式氧合器的设计是作者在国外建立的交叉流式膜肺Ｏ２、ＣＯ２传递模型的具体应用。

The design and laboratory manufacture of "SUU TYPE Ⅰ"extra luminal flow(ELF) hollow fibre membrane oxygenator are presented.The design is based on the O 2 and CO 2 transfer models in the cross flow membrane oxygenator of Mockros and Pei.This paper also introduces the sketch of the membrane oxygenator,the structure of housing,the bundle of hollow fibres and the procedure of centrifugal potting.The self made potting equipment and process of centrifugal potting are emphasized.The key know how of centrifugal potting includes:(1) assuring the quality of the hollow fibre membrane material and the bundle;(2)calculating the quantity of potting material,polyurethane;(3) controlling reaction temperature;(4)removing gas from potting ends;(5)controlling rotation speed;(6)inserting the bundle in the house;(7)mastering the time of demoudling and cutting.