人体硬组织替代材料表面吸附白蛋白方法的研究

Study on the Method of Adsorbing Albumin for Enwrapping Human Hard Tissue Substitute Biomaterials

采用戊二醛交联法，对吸附在羟基磷灰石（ＨＡ）、生物玻璃陶瓷（ＢＧＣ）和羟基聚磷酸钙钠（ＨＰ）表面的白蛋白进行交联，使蛋白质互相交联形成一层蛋白膜，达到在材料表面较为牢固地吸附一层蛋白质的目的。结果表明该方法可以使蛋白质牢固地吸附在材料表面，不能被尿素溶液所洗脱。

The aim of this study was to cover up the surface of human hard tissue substitute biomaterials with albumin.The cidex cross link method was adopted to adsorb albumin so as to form a membrane for wrapping hydroxyapatite(HA),bio glass ceramics(BGC),and hydroxyl poly calcium sodium phosphate(HP).The results showed that this membrane of protein could enwrap the biomaterials so firmly that urea solution could not wash it off.