摘要
目的观察间苯三酚舌下含服治疗急性胃肠痉挛性腹痛的疗效及安全性。方法将250例急性胃肠痉挛性腹痛患者随机分为两组:山莨菪碱组(125例,给予山莨菪碱针10 mg肌肉注射)和间苯三酚组(125例,给予间苯三酚口服冻干片80 mg舌下含服)。观察两组用药10 min后的止痛效果、腹痛开始缓解时间及不良反应发生情况。结果两组患者用药10 min后的止痛效果及腹痛开始缓解时间比较,差异均无统计学意义(P>0.05);但两组不良反应发生率间差异有统计学意义(P<0.01)。结论间苯三酚舌下含服治疗急性胃肠痉挛性腹痛的疗效与山莨菪碱相当,但不良反应的发生率较低,且给药方便。
Objective To evaluate the efficacy and security of sublingually - administered phloroglucinol in treating acute spastic abdominal pain from stomach and intestines. Methods Two hundred fifty patients were randomly divided into 2 groups. The control group （n = 125 ） were given an intramuscular injection of anisodamine （10 rag） , and therapy group （n = 125 ） given sublingually phloroglucinol oral lyophilisates 80 rag. The analgesia efficacy, the starting time of abdominal pain release and the side effects were analyzed 10 minutes after administration. Results There was no significant difference in analgesia efficacy （ P 〉 0. 05 ） , and in starting time of abdominal pain release （ P 〉 0. 05 ） , but there was in the side effects between two groups （ P 〈 0.01 ）. Conclusion Sublingually- administered phloroglucinol is effective and safe in treating acute spastic abdominal pain from stomach and intestines.
出处
《中国全科医学》
CAS
CSCD
北大核心
2009年第4期305-306,共2页
Chinese General Practice
关键词
间苯三酚
投药
舌下
山莨菪碱
腹痛
疗效
Phloroglucinol
Administration, sublingually
Anisodamine
Abdominal pain
Efficacy
