多囊卵巢综合征患者生存质量分析

Quality of life in patients with polycystic ovary syndrome

对2008年1月至4月就诊的116例多囊卵巢综合征（PCOS）患者行健康状况问卷（SF-36）、焦虑自评量表评分（SAS）、抑郁自评量表评分（SDS）调查，评价患者生存质量（QOL）状况及相关影响因素。与健康对照者比较，PCOS患者SF-36评分中除躯体疼痛、生理职能差异无统计学意义外，其他6项评分均明显降低（均P〈0．05）；SAS、SDS评分明显高于健康对照者（P〈0．01）。提示PCOS患者QOL多个维度均有受损，不孕、肥胖、多毛、痤疮、有合并症、月经紊乱及文化程度高低等均可影响其QOL。

A cross-sectional study in 116 patients with polycystic ovary syndrome （PCOS） was carried out by using the short-form-36 health survey （ SF-36）, self-rating anxiety scale （ SAS）, and self-rating depression scale （SDS） from January 2008 to April 2008 in our reproduction center. In comparison with the healthy controls, the PCOS patients showed decreased quality of life （QOL） for all items of SF-36 （ P 〈 0. 05 ） except for body pain or role-physical scales. The differences in SAS and SDS between the PCOS and the healthy controls were statistically significant （ P 〈 0.05 ）. Our study results confirm the negative impacts of PCOS over the quality of life; subfertility, obesity, hirsutism, acne, complications, menstrual irregularity and educational levels might contribute to the reduced QOL.