二尖瓣狭窄下游流场均匀性的多普勒超声研究

Study of Flow Field Uniformity Downstream of Mitral Stenosis Using Doppler Echocardiography

为探讨二尖瓣病变及其狭窄程度与下游流场均匀性之间的关系，采用先进的彩色多普勒超声技术，对６０例不同程度二尖瓣狭窄患者二尖瓣下游流场均匀性进行了体内定量研究，并与２０例健康受试者相比较。结果显示：二尖瓣病变严重程度与其狭窄程度及下游流场均匀性之间存在线性关系，二尖瓣病变越重，狭窄越明显，流场均匀性越差。由此提示，心瓣膜下游流场均匀性及湍流剪应力与瓣膜损害之间可能存在某种互为因果的关系。

To research into the relationship between mitral lesion, stenosed degree and flow field uniformity downstream of mitral valve, we adopted the advanced color Doppler echocardiographic technique to conduct a quantitative study of flow field uniformity downstream of mitral valve in sixty patients with varying degree of mitral stenosis in vivo. Twenty normal persons acted for comparison. The results showed that there was a linear correlation between the extent of valvular lesion, the stenosed degree and flow field uniformity downstream of mitral valve. We conclude that the more severe the mitral lesion is, the more grave the stenosis is and the worse the flow field uniformity is. This suggests that there might be a reciprocity between valvular lesion and flow field uniformity as well as turbulent shear stress, which should be further studied.