脂肪乳剂对肝脏疾病患者术后血脂、载脂蛋白、LCAT、KBR的影响

Effects of Fat Emulsion on Serum Lipid, apo AⅠ,apo B100, LCAT, KBR of Postoperative Patients with Liver Disorder

为了解脂肪乳剂对肝脏疾病术后血脂、载脂蛋白、胆固醇酯酰转移酶（ＬＣＡＴ）、酮体比的影响，将２０例肝脏外科疾病患者术后随机分成２组，第１组（ｎ＝１０）平均输注０８２ｇ·ｋｇ－１·ｄ－１脂肪乳剂，占总热卡４２％；第２组（ｎ＝１０）平均输注１７２ｇ·ｋｇ－１·ｄ－１，占总热卡５２％。行短期术后营养支持５天，观察血脂、载脂蛋白、ＬＣＡＴ、酮体比及脂肪廓清等的变化。结果提示肝脏疾病致肝功能轻、中度异常时。

Twenty post operative patients with liver disorder were divided randomly into two groups. Ten of them received mean 0.82g·kg -1 ·d -1 fat emulsion(42% of the total calorie),and the other ten received mean 1.72g·kg -1 ·d -1 fat emulsion (52% of the total calorie)via vein during 5 post operative days.Their serum lipid,apoAⅠ,apoB100,ketone body ratio(KBR),fat clearance,LCAT and so on were investigted.The results suggest that it is safe for liver disordered patients with slight or even moderate abnormality of liver function to receive mean 0.82g·kg -1 ·d -1 and 1.72g·kg -1 ·d -1 fat emulsion after operation and the use of mean 1.72g·kg -1 ·d -1 fat emulsion will do no harm but good to liver function.