C-反应蛋白对儿科细菌感染性疾病的临床诊断价值

Clinical diagnostic value of C-reactive protein in paediatric infectious diseases caused by bacteria

目的探讨血清C-反应蛋白(CRP)检测在儿童细菌性感染疾病的诊断价值。方法(1)用HITA-CHI日立7600全自动生化分析仪检测82例细菌感染患儿(观察组)及30例健康儿(对照组)的血清CRP含量。(2)用血细胞计数仪ABX-PENTRA60对以上82例细菌感染患儿(观察组)及30例健康儿(对照组)进行白细胞计数。(3)将以上两种方法做统计学比较。结果观察组各种疾病的CRP检测值均显著高于对照组(P<0.001),82例患儿中,CRP阳性78例,阳性率95.1%;白细胞水平升高64例,阳性率78.0%,两种检测阳性率差异有统计学意义(P<0.01)。结论CRP检测对儿科细菌性感染疾病的诊断和治疗有一定的临床应用价值,可以作为诊断小儿细菌性感染和观察治疗效果的敏感指标。

Objective To study the clinical diagnostic value of C-reactive protein （CRP） in paediatric infec tious diseases caused by bacteria. Methods Eighty-two cases of bacterial infection （observation group） and thirty cases of healthy children （control group） were enrolled in the study. Serum concentration of CRP was measured with HITACHI 7600 Automatic Biochemical Analyzer; WBC count was performed with ABX-PENTRA60 Hematology Analyzer. The results were compared and analyzed between the two groups. Results The level of CRP was obviously higher in observation group than that in control group （P〈0. 001）. In observation group, the positive rate of CRP was 95.1% （78/82）,and 64 cases （78.0%） were WBC elevated; there was statistical difference of positive rate between CRP and WBC measurement methods （P〈0.01）. Conclusion CRP is valuable in the diagnosis of paediatric infectious diseases caused by bacteria and may be a sensitive index of paediatric diagnosis and curative effect observation.