摘要
免疫亲和膜是基于抗原和抗体间高特异性可逆相互作用对抗体或抗原进行分离的一项新型分离技术,兼有膜分离和亲和色谱的优点.介绍了免疫亲和色谱的作用机理、膜材料和配体的选择,以及免疫亲和膜在抗体分离纯化和快速诊断测试方面的应用,同时还对免疫亲和膜的未来发展进行了展望.
Immuno- affinity membrane separation is a new technology based on the specific interaction of antibody and antigen, which could separate antibody or antigen efficiently. It possesses both advantages of membrane separation and affinity chromatography. This article illustrates the mechanism of immuno - affinity membrane, the selectivity of membrane material and ligands, and its application in antibody purification and rapid detection test. The existing problem and the expectation are also mentioned in this article.
出处
《膜科学与技术》
CAS
CSCD
北大核心
2009年第1期90-95,共6页
Membrane Science and Technology
关键词
亲和膜
免疫亲和
抗体
抗原
affinity membrane
immuno - affinity
antibody
antigen