翻白草化学成分的研究

Studies on the Chemical Constituents of Potentilla discolor Bge

目的研究翻白草的化学成分。方法用硅胶柱色谱、凝胶柱色谱等多种柱色谱分离,得到单体化合物,用各种有机波谱鉴定化合物结构。结果分离得到6个化合物,鉴定为坡模酸(pomolic acid,1),3-O-乙酰坡模醇(3-O-acetyl-pomolic acid,2),齐墩果酸(oleanolic acid,3),2α-羟基白桦酯酸(2α-hydroxyl betulinic acid,4),槲皮素-3-O-β-D-葡萄糖(quercetin-3-O-β-D-glucoside,5),山萘酚-3-O-β-D-葡萄糖(kaempferol-3-O-β-D-glu-coside,6)。结论所有化合物均为首次从翻白草中分离得到。

Objective To study the chemical constituents of Potentilla discolor. Methods Chemical constituents were isolated by repeated column chromatographies. The structures were elucidated on the basis of spectral data analysis. Results Sis compounds, pomolic acid（ 1 ）, 3 - 0 - acetyl - pomolic acid （2）, oleanolic acid（3 ）, 2α- hydroxyl betulinic acid （4）, quercetin - 3-O-β-D-glucoside （5）, kaempferol -3-O-β-D- glucoside （6） were isolated from P. discolor. Conclusion All the compounds were isolated from the plant for the first time.