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血浆N末端脑钠肽原与高血压的关系

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摘要 目的探讨高血压患者血浆N末端脑钠肽原(NT-proBNP)浓度与高血压程度是否相关,以及NT-proBNP能否作为高血压严重程度的客观生化指标。方法入选2006年9月—2007年6月,在我院门诊及住院的高血压患者共115例。采集静脉血样的同时对高血压患者进行分级,通过心电图、心脏超声及临床表现进行左室心功能评估。用电化学发光免疫学法检测血浆NT-proBNP浓度。结果1级、2级高血压组与正常对照组间的NT-proBNP浓度差异无统计学意义(P>0.05);3级高血压组比正常对照组的NT-proBNP浓度高(P<0.05);高血压伴收缩性心力衰竭患者血浆NT-proBNP浓度高于单纯高血压患者(P<0.01)。结论高血压患者血浆NT-proBNP浓度与高血压程度有一定关系,与高血压伴收缩性心力衰竭相关性强。NT-proBNP可能会成为评估高血压疾病严重程度的生化指标之一。
出处 《中西医结合心脑血管病杂志》 2009年第2期223-224,共2页 Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
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