臂踝脉搏波传播速度与急性冠脉综合征患者冠脉病变的关系研究

Relationship between the brachial ankle pulse wave velocity and the stricture of coronary artery in acute coronary syndrome

目的探讨急性冠脉综合征(ACS)患者中臂踝脉搏波传播速度(brachial ankle pulse wave ve-locity Ba-PWV)水平与冠心病危险因素和冠状动脉狭窄程度的相关性。方法将74例ACS患者分为Ba-PWV<1400cm/s组(20例)和Ba-PWV>1400cm/s组(54例)。分析2组中年龄、性别、高血压、高脂血症、糖尿病、吸烟等冠心病危险因素以及冠脉血管狭窄程度。结果(1)Ba-PWV>1400cm/s组患者的危险因素明显多于Ba-PWV<1400cm/s组(P<0.05),其中≥2个危险因素的患者在Ba-PWV>1400cm/s组中高达96.3%(P<0.01);(2)Ba-PWV>1400cm/s组冠脉狭窄程度与Ba-PWV<1400cm/s组比较差异无统计学意义。结论发生ACS时,Ba-PWV大的ACS患者其危险因素多于Ba-PWV小者,Ba-PWV与相关冠脉狭窄严重程度不相关。

Objective To explore the relationship between the brachial ankle pulse wave velocity （Ba- PWV）level and high risk factors of coronary heart disease and stricture of coronary artery in acute coronary syndrome（ACS）. Methods Seventy four cases of ACS were divided into two groups： twenty eases with Ba-PWV〈 1400cm/s and fifty four cases with Ba-PWV〉 1400 cm/s. Risk factors of coronary heart disease were analyzed such as age, gender, hypertension, hyperlipidemia, diabetes mellitus and smoking and stricture of coronary artery in two groups. Results （1）In group with Ba-PWV〉1400cm/s, the risk factors of coronary heart disease was more than that in group with Ba-PWV〈 1400cm/s, P 〈 0.05, the risk factors were no less than two in 96.3% of cases, P 〈0.01. （2）There was no statistics difference in the stricture degree of coronary artery between two groups. Conclusion The risk factors in the cases with high Ba-PWV levels are more than those in the cases with low Ba-PWVjevel in ACS. There was no relativity between the Ba-PWV and the stricture degree of mrresponding coronary arteries in ACS.