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卢戈氏染色诊断食管早期癌和表浅癌价值的评价 被引量:51

EVALUATION OF LUGOL' S STAINING IN DETECTING EARLY,SUPERFICIAL CANCER OF ESOPHAGUS
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摘要 为了再度评价卢戈氏液内镜下食管粘膜染色对食管早期癌和表浅癌的诊断价值,对144例食管早期癌可疑患者进行食管粘膜染色,并对不染区多点活检送病理检查,其中131例为肉眼无可疑病灶者,94例没有任何食管症状。诊断结果:食管癌7例(手术证实粘膜癌2例,粘膜下癌2例);不典型增生10例(轻度5例,中度3例,重度2例);单纯上皮增生伴或不伴慢性炎症25例;结核1例。并发现有食管症状者碘不染区出现率明显高于无食管症状者(P<0.05)。结论:内镜下卢戈氏液染色有助于食管早期癌、表浅癌及癌前病变的诊断。 Lugol's solution was adopted to stain esophageal mucosa in 144 cases with suspected early malignancy for its diagnostic value.From unstained areas (n=79) multiple biopsies were taken for pathology.Which revealed 7 cancers (2 mucosal,2 submucosal,1 subserosal,2 uncertain),10 dysplasias (5 mild,3 moderate,2 severe),25 proliferations±inflammation and 1 tuberculosis.The incidence of iodine unstained area in cases with symptoms maintained significantly higher than those without (P<005).It is assumed that Lugols staining is an useful aid to set early,superficial esophageal cancer diagnosis and helpful to differentiate from precancerous lesions.
出处 《中华消化内镜杂志》 1998年第3期142-144,共3页 Chinese Journal of Digestive Endoscopy
关键词 卢戈氏液染色 食管肿瘤 诊断 Esophageal cancer Lugols staining
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参考文献4

  • 1Nothmann,E.J.,Wright J.R.,Schuster,M.M.In vivo vltal staining as an aid to identification of esophageal and gastric mucosal juntion in man. Digest. Dis.,1972,17:919.
  • 2Akaska,Y,Okuda,S.,Ida,K.Basic Research and clinical application in esophagoscopic Lugol's staining. Gastroenterol,Endose.,1974,18-84.
  • 3Ide H.,Endo M.Intramural metastasis and multiple lesions in esophgeal cancer. In"Geka Mook 24"ed.by M.Endo.Kanehara Co.Tokyo,1982,128.
  • 4Guanrei Y,He H,Sungliang Q,et al. Eneoscopic diagnosis of 115 cases of early esophageal carcinoma. Endoscopy,1982,14:157.

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