摘要
测定70例斑秃患者血清肿瘤坏死因子-α(TNFα)水平。测定结果示斑秃患者TNFα明显高于对照组(P<0.01)。活动期患者明显高于静止期(P<0.01)。而单纯斑秃组与全、普秃组相比,则无明显差异(P>0.05)。表明斑秃患者存在着免疫功能异常,并与斑秃的发病及病情活动有关。
Serum TNFα levels were detected in 70 cases of alopecia areata (AA). The results showed that TNF-a level of the patients was obviously higher than that of controls (P < 0. 01 ), and the level was significantly higher in active stage than that in stead}stage (P < 0. 01 ), There were no obvious differences (P > 0. 05) in the levels of TNFα among AA, alopecia totalis and alopecia universalis groups. It suggests that the immunologic function of AA patients is abnormal, which may play a role in the pathogenesis of alopecia areata and disease activity.
出处
《临床皮肤科杂志》
CAS
CSCD
北大核心
1998年第3期160-161,共2页
Journal of Clinical Dermatology