更昔洛韦联合氦-氖激光治疗带状疱疹神经痛疗效观察

Curative Effects of Ganciclovir Combined with He-Ne Laser for Herpes Zoster Neuralgia

目的探讨更昔洛韦联合氦-氖激光治疗带状疱疹的临床疗效。方法治疗组44例,给予更昔洛韦0.25g,每日1次,静脉滴注,联合氦-氖激光治疗,每天1次,共7d。对照组32例,给予更昔洛韦0.25g,1次/d,共7d。结果治疗组治愈12例,显效29例,无效3例,总有效率93.18%;对照组治愈7例,显效17例,无效8例,总有效率75.00%。治疗组总有效率明显高于对照组(χ2=4.947,P<0.05)。结论更昔洛韦联合氦-氖激光治疗带状疱疹神经痛的疗效迅速,病情恢复良好。

Objective To study the curative effects of ganciclovir combined with He-Ne laser for herpes zoster neuralgia. Methods 76 cases with herpes zoster neuralgia were randomly divided into two groups. Group A （ treatment group, n = 44） were administered with 0.25g Ganciclovir by intravenous injection combing with Helium-Ne laser once daily, while group B （control group, n = 32） only with 0.25g Ganiclovir once daily. The course of treatment was 7 days in both groups. Results In group A, 29 cases were healed,17 cases achieved obvious effect,3 cases no effect with a total efficient rate was 93.18%. In group B,7 cases were healed, 17 cases achieved obvious effect and 8 cases no effect with a total efficient rate of 75%. The difference was obviously between the both groups （ X^2 = 4. 947, P 〈 0.05 ）. Conclusion Ganciclovir combined with He-Ne laser can control the herpes zoster neuralgia rapidly with good recovery.