老年护理院细菌性尿路感染菌群及耐药性分析

Analysis of Bacterioflora and Drug Resistance in Patients with Bacterial Urinary Tract Infection in Aged Nursing Home

目的了解老年护理院患者细菌性尿路感染的菌群分布及耐药性,为临床治疗提供依据。方法回顾性分析我院老年护理病房住院患者中尿路感染138例患者的菌群分布和药敏结果。结果共收集致病菌158株,其中革兰氏阴性杆菌感染109株(69.00%),革兰氏阳性球菌49株(31.00%)。革兰氏阴性杆菌中大肠埃希菌检出率最高(64株,58.72%),革兰氏阳性球菌以粪肠球菌最多见(24株,48.98%),药敏结果显示革兰氏阴性杆菌对氨基糖甙类抗生素的耐药率低,其次为三代头孢菌素;革兰氏阳性球菌对万古霉素耐药率低。结论革兰氏阴性杆菌是老年护理院患者细菌性尿路感染的主要病原菌,应依据尿细菌培养和药敏结果选用敏感抗生素。

Objective To investigate the bacterial distribution and antibiotic resistance of bacteria in aged nursing home patients with bacterial urinary tract infection,so as to provide the basis for clinical treatment. Methods The bacterial distribution and antibiotic resistance of bacteria in 138 patients with bacterial urinary tract infection in aged care wards in our hospital were analysed retrospective. Results 158 pathogens were isolated from these patients, including gram-negative bacillus（ 109 cases, 69.00% ）, gram-positive cocci （49 cases, 31.00% ）. In Gram-negative bacilli, most were Escherichia coli （ 64 cases, 58.72% ）, Most Gram-positive cocci were Enterococcus faecalis（24 cases 48.98% ）. Drug resistance rate of gram-negative bacilli to aminoglycoside antibiotics was the lowest, the second was third-generation cephalosporins;Resistance of Gram-positive cocci to vancomycin was low. Conclusion Gram-negative bacilli （ mainly Escherichia coli） are main pathogens of patients with bacterial urinary tract infection in aged nursing home, the using of antibiotics must be based on drug sensitivity test.