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角蛋白与肝脏疾病 被引量:1

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摘要 肝细胞富含角蛋白(keratin,K),它是细胞骨架蛋白中间丝家族的最重要和最大的成员,不仅有重要的细胞保护功能而且也与人类疾病密切相关,研究已经表明角蛋白基因变异是某些皮肤及其附属器、口腔和角膜疾病的直接病因,近年也发现角蛋白基因变异是肝脏病发病的易感性因素^[1-4]。
出处 《中华医学杂志》 CAS CSCD 北大核心 2009年第4期280-282,共3页 National Medical Journal of China
基金 广东省科技计划项目(2004850301015)
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