TORCH-IgM阳性已婚拟孕妇女的影响因素分析

An analysis of impact factors for TORCH IgM positive pre-pregnancy married women

目的调查江苏省18个项目点已婚拟孕妇女TORCH感染状况及婚育和生活状况,分析其与TORCH-IgM阳性之间的关系。方法用预先设计好的调查表对TORCH-IgM筛查妇女进行人口特征、文化程度、职业、婚姻、生育状况、有无遗传性疾病和生活状况调查。结果TORCH-IgM筛查结果阳性组工人和无业者构成比分别为38.1%(609/1600)和9.3%(148/1600),高于阴性组,阴性组分别为32.1%(645/2010)和7.4%(149/2010),阳性组农民和亦工亦农的构成比分别为24.1%(386/1600)和4.1%(65/1600),低于阴性组,阴性组分别为28.9%(580/2010)和8.3%(166/2010),差异有统计学意义(P<0.05),阳性组和阴性组接触宠物者分别占调查人数的29.9%(447/1611)和6.3%(127/2012),阳性组比阴性组妇女接触宠物多4.75倍,差异有统计学意义(P<0.0001)。结论妇女TORCHIgM阳性和生活中密切接触宠物及职业有关。

Objective To understand the percentage of women with positive IgM for TORCH （ab- breviation of Toxoplasma gondii, others virus, Rubella virus, Cytomegalo virus and Hespes simplelvimstypes virus Ⅰ and Ⅱ） and its association with selected characteristics of living, marriage and fertility among pre-pregnancy married women. Methods 18 000 pre-pregnancy married women from 18 sites in Jiangsu Province were investigated for IgM of TORCH . Among them 1611 who were IgM positive were further investigated and analyzed for their status of living , marriage and fertility. 2 012 IgM negative women were selected as controls. Questionnaires were designed to survey the demographic characteristics, education background, occupation, hereditary diseases, living conditions and marital status, menses and fertility. Results Among the women who were IgM positive in TORCH screening, the percentage of workers and the jobless was 38. 1% （609/1 600） and 9.3 % （148/1 600）, which was significantly higher than that among control group, 32. 1% （645/ 2 010） and 7. 4 % （149/2 010）. The percentage of peasants and the people being both worker and peasant was 24. 1% and 4. 1% （65/1 600 ） among the positive group, which was lover than that among control women, 28. 9 % （580/2 010） and 8. 3 % （166/2 010） （P 〈0. 05）. The rate of pet contacting was 29. 9 % （447/1 611） for the positive group and was about 4. 75 times higher than that for control group, 6. 3 % （ 127/2 012）. The difference was statistically significant （P 〈 0. 0001 ）. Conclusion The positive IgM in TORCH screening of women is related to their occupation and close pet contacting in daily life.