败血症患儿厌氧血培养639例

Anaerobic blood culture in 639 children.

目的开展败血症患儿厌氧血培养，提高病原菌检出率。并分析患儿厌氧菌败血症的主要特点。方法应用ＡＰＩ２０Ａ鉴定系统对厌氧血培养分离的厌氧菌种进行鉴定。结果６３９例败血症患儿中，厌氧菌单独阳性３１例（４．８％），需氧菌单独阳性４４例（６．９％），两者同时阳性２０例（３．１％）。合计厌氧菌阳性检出率为８．０％（５１／６３９）。脆弱类杆菌致患儿厌氧菌败血症１２例。结论开展小儿厌氧血培养可提高败血症的病原菌阳性检出率及临床诊治水平；易合并肺炎、支气管肺炎和高胆红素血症，是厌氧菌败血症患儿的两个主要特点。

Objective To detect the pathogen component and analyze the major characteristics of children′s anaerobic septicemia. Methods Anaerobes isolated from anaerobic blood culture were identified using API system. Statistical analysis of the complications of anaerobic septicemia was made. Results In anaerobic culture of blood samples of 639 children, 31 (4.8%) showed anaerobe positive results, 44 (6.9%) aerobe positive, 20 (3.1%) both positive. The total detection rate of positive anaerobe was 8.0% (51/639). B.fragilis was the main infective bacterium of anaerobic septicemia in children (12 cases). Conclusion Pneumonia, bronchitis (58.8%) and hyperbilirubinemia are the complications of children′s anaerobic septicemia. Anaerobic blood culture can improve the positive pathogenic detection rate of septicemia and the level of clinical diagnosis and treatment.