摘要
目的探讨CT灌注成像在肝癌TACE术后活性灶评估中的应用价值。方法30例行TACE治疗的肝癌患者,术后均行肝脏CT平扫、CT灌注成像及常规肝增强扫描并以三者作为术后影像学随访的手段。根据灌注扫描所得图像自动生成时间-密度曲线(TDC),计算灌注参数。包括:血流量(BF)、血容量(BV)、对比剂的平均通过时间(MTT)、毛细血管通透性(PS)和肝动脉指数(HAI)。以再次肝动脉造影结合临床随访作为"诊断金标准"进行临床诊断试验与评价。结果TACE术后肝癌活性灶与非瘤区肝组织的BF,BV,MTT,HAI具有显著统计学差异(P<0.05)。PS无显著统计学差异(P>0.50)。CTP的诊断正确率=91.07%;灵敏度=95.74%;特异度=66.67%;阳性预测值=93.81%;阴性预测值=75.00%;阳性似然比=2.74;阴性似然比=0.13;Youden指数=57.82%。结论CT灌注成像在肝癌TACE术后活性灶评估中具有较高的应用价值。
Objective To evaluate 16 multi-slice spiral CT perfusion imaging (CTPI) in the following up of hepatocellular carcinoma (HCC)after transcatheter arterial chemoembolization (TACE). Methods Thirty patients suffered from HCC after TACE underwent multi-slice spiral CTPI, and the outcomes were compared with DSA or pathologic findings. Results CTPI had the accuracy of 91.07%, sensitivity of 95.74%, specificity 66.67% and Youden's index of 57.82% in detecting the newborn blood supplies and/or the residual blood supplies. Conclusion Multi-slice CTPI is a noninvasive evaluating and following up method for HCC after TACE.
出处
《中国介入影像与治疗学》
CSCD
2009年第1期63-66,共4页
Chinese Journal of Interventional Imaging and Therapy
关键词
肝肿瘤
体层摄影术
X线计算机
栓塞
治疗性
Liver neoplasms Tomography, X-ray computed Embolization, therapeutic