2种口服对比剂在MRCP成像中的临床应用价值

Ferric ammonium citrate solution versus Gd-DTPA dilution as oral contrast agent for MRCP image

目的比较2种口服对比剂在MRCP成像中的临床应用价值,探讨一种安全性、效价比俱佳的胃肠道阴性口服对比剂,改善MRCP图像的质量。方法根据行MRCP检查时口服对比剂稀释液的不同将患者分为2组,A组30例口服枸橼酸铁铵稀释液,B组30例口服钆喷酸葡胺(Gd-DTPA)稀释液,MRCP扫描采用带脂肪抑制的半傅立叶采集厚层单次激发快速自旋回波(T2-haste-fs-thick-slab)序列。评价同一病例口服对比剂前后2次MRCP扫描的图像资料。结果2组病例口服对比剂溶液后胃肠道液体干扰影基本得到完全抑制,口服对比剂溶液后MRCP图像质量明显提高,肝内外胆管及胰管的显示效果均达到2级以上水平,比较使用2种不同对比剂溶液后的MRCP图像质量无明显差别。结论枸橼酸铁铵泡腾颗粒稀释液和静脉用钆喷酸葡胺(Gd-DTPA)稀释液二者均是有效的胃肠道口服阴性对比剂,钆喷酸葡胺(Gd-DTPA)稀释液更加经济实惠、性价比较高。

Objective To compare the clinical value of 2 oral contrast agents for magnetic resonance cholangiopancreatography （MRCP） and to investigate the safety, potency ratio of negative gastrointestinal contrast agents and to improve MRCP image quality. Methods Before MRCP, 30 patients took oral ferric ammonium citrate （FAC） solution as group A and another 30 patients took Gd-DTPA dilution as group B. Then all patients underwent MRCP with T2-haste-fs-thick-slab sequence. Image assessment was done before and after oral taking of negative gastrointestinal contrast agents. Results After oral taking of negative gastrointestinal contrast agents, the interference of liquid in stomach and duodenum was suppressed and even effectively eliminated on MRCP. MRCP image quality was improved. Though the display of bile duct and pancreatic duct was of less image artifact, it reached the quality for diagnosis. No significant difference of MRCP image quality was found between those took FAC solution or Gd-DTPA solution. Conclusion FAC and Gd-DTPA both are effective negative gastrointestinal contrast agents. Gd-DTPA solution is of better function and higher quality-price ratio.