同种异体肌腱移植的前景及问题

Advances and problems in allograft tendon transplantation

由于自体肌腱移植来源有限,组织工程化肌腱尚难以真正应用于临床,同种异体肌腱移植是目前修复肌腱缺损尤其是多条肌腱缺损较为理想的方法。国内外学者对异体肌腱的获取、保存、处理、免疫学特性、临床应用和预后方面做了大量的研究工作,使异体肌腱移植技术日臻完善。同种异体肌腱移植已越来越多的应用于修复人体腱性组织缺损,但是异体肌腱的处理、免疫学特性以及移植后机械强度、术后粘连等问题还需要进一步解决。

Given the limited sources of autogenic tendon and the difficulties of the tissue engineering tendon to clinical application, the allograft tendon transplantation was a good way for tendon repairing defects. The domestic and foreign scholars have done a lot of studies on the acquisition, preservation, immunological characteristics, clinical application and prognosis of allograft tendon transplantation technology. The allograft tendon transplantation has been more and more used to repair the tendon tissue defects, but there still were some problems to be solved, such as the preservation, immunological characteristics, mechanical strength and postoperative adhesions.