短期持续皮下胰岛素输注强化治疗糖尿病的临床观察

Intensive therapy of 15 cases diabetes mellitus with continuous subcutaneous insulin infusion

目的:观察持续皮下胰岛素输注法(CSII)对糖尿病患者强化血糖的控制效果。方法:35例糖尿病患者随机分为CSII组(15例)和常规多次皮下注射法(MDI)组(20例),进行强化胰岛素治疗。结果:CSII组血糖控制达标的时间和胰岛素的用量明显少于MDI组;CSII组的低血糖的发生率较低,并且能较有效地控制黎明现象的发生。结论:CSII是短期糖尿病患者强化血糖控制较理想的方法。

OBJECTIVE To investigate the effect of intensive therapy with continuous subcutaneous insulin infusion（CSII） on diabetes mellitus. METHODS 35 cases diabetes mellitus were randomly divided into CSII group（15 cases） and MDI（multipie daily injection） group（20 cases）. RESULTS The time when the goal of boold glucose control was achieved, in CSII group was shorter than in MDI group,and the total insulin dose in CSII group was lower than in MDI group; the rate of hypoglycaemia and down phenomenon in CSII group was lower than in MDI group. CONCLUSION CSII is a ideal method of intensive glucose control in diabetes.