白细胞介素-21及其受体与相关疾病的研究进展
摘要
白细胞介素-21(IL-21)具有广泛的免疫调节生物学功能,而这些功能的发挥又必须依赖其受体(IL-21R)的存在和协同作用。IL-21与IL-21R结合后,通过细胞内JAK/STAT信号传导通路,并将信号传导给下游效应分子,促进B细胞的增殖分化,免疫球蛋白的生成;
出处
《现代检验医学杂志》
CAS
2009年第1期140-142,共3页
Journal of Modern Laboratory Medicine
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