受血者输血前不同人群梅毒抗体流行情况调查

Investigation and study on prevalence of syphilis among different blood recipients before transfusion

目的:检测受血者梅毒感染率流行情况及其危险因素,为安全输血提供保障,减少因输血引起的医疗纠纷。方法:选择2005-2007年34209例需输血及术前备血的患者,进行梅毒螺旋体血凝实验(TPPA)已确诊。结果:梅毒抗体阳性率0.57%(196/34209),其中女性梅毒抗体阳性率0.48%(94/19527),男性梅毒抗体阳性率0.69%(102/14682),差异有统计学意义(P<0.05);各年阳性率分别为0.46%、0.51%、0.73%,采用2005年与2006年比较,(P>0.05)差异无统计学意义;2006年与2007年比较(P<0.05),差异有统计学意义。小于20岁、20～50岁、50岁以上不同年龄段阳性率构成比分别为2.04%、70.92%、27.04%。结论:受血者梅毒感染率逐年升高,男性患者明显高于女性,通过对受血者梅毒抗体检测,可明确患者健康状况,杜绝医源性经血液传播疾病而引起的医疗纠纷,保护医患双方的的利益。

Objective：To investigate the prevalence of syphilis and risk factors in blood recipients in order to ensure safe transfusion. Method：34 209 blood recipients during 2005 - 2007 were selected and syphilis were detected by TPPA. The statistic analysis method was X^2 test. Result： The positive rate of syphilis was 0.57% （196/ 34209）. The positive rate of syphilis in female and male blood recipients were 0.48% （94/19527） and 0. 69 % （102/ 14682）, respectively. There was a significant difference （X^2= 6.61, P〈0.05）. The positive rate of syphilis in 2005,2006 and 2007 were 0.46%, 0.51 % and 0.73%, respectively. There was a significant difference between 2006 and 2007（X^2 = 4.53, P〈0.05）. Conclusion： The prevalence of syphilis in blood recipients was increasing yearly. With the syphilis detection in patients before transfusion, we can identify the patient＇s health state, avoid the medical dispute resulted from the iatrogenic blood transmitted diseases and eventually protect the benefits of both patient and medical personnel.