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强化血糖控制与大血管疾病的预防:解析ACCORD,ADVANCE及VADT研究结果——美国糖尿病协会、美国心脏病学会基金会及美国心脏协会的立场声明 被引量:3

Intensive glyeemic control and the prevention of cardiovascular events : implications of the ACCORD, ADVANCE, and VA Diabetes Trials
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摘要 本文对“Intensive glycemic control and the prevention of cardiovascular events: implications of the ACCORD, ADVANCE, and VA Diabetes Trials: a position statement of the American Diabetes Association and a scientific statement of the American College of Cardiology Foundation and the American Heart Association”进行了翻译整理。 This article introduces the main ideal of “Intensive glycemic control and the prevention of cardiovascular events: implications of the ACCORD, ADVANCE, and VA Diabetes Trials: a position statement of the American Diabetes Association and a scientific statement of the American College of Cardiology Foundation and the American Heart Association”.
出处 《国际内分泌代谢杂志》 2009年第1期68-72,共5页 International Journal of Endocrinology and Metabolism
关键词 2型糖尿病 心血管疾病 强化血糖控制 ADVANCE ACCORD VADT Type 2 diabetes mellitus Cardiovascular diseases Intensive glycemic control ADVANCE ACCORD VADT
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  • 1田晨光.灵活使用双时相门冬胰岛素30治疗2型糖尿病[J].中华糖尿病杂志,2010,2(4). 被引量:2
  • 2Nathan DM,Cleaiy PA,Backlund JY,et al.Intensive diabetes treatment and cardiovascular disease in patients with type 1 diabetes.N Engl J Med,2005,353:2643-2653.
  • 3Tonna S,E1-Osta A,Cooper ME,et al.Metabolic memory and diabetic nephropathy:Potential role for epigenetic mechanisms.Nat Rev Nephrol,2010,[Epub ahead of print] .
  • 4Ihnat MA,Thorpe JE,Ceriello A.Hypothesis; The "metabolic memory",the new challenge of diabetes.Diabet Med,2007,24:582-586.
  • 5Rosca MG,Mustata TG,Kinter MT,et al.Glycation of mitochon-drial proteins from diabetic rat kidney is associated with excess superoxide formation.Am J Physiol Renal Physiol,2005,289:F420-F430.
  • 6Chan PS,Kanwar M,Kowluru RA.Resistance of retinal inflammatory mediators to suppress after reinstitution of good glycemic control:Novel mechanism for metabolic memory.J Diabetes Complications,2010,24:55 -63.
  • 7Kowluru RA,Kanwar M.Kennedy A.Metabolic memory phenom-enon and accumulation of peroxynitrite in retinal capillaries.Exp Diabetes Res,2007,2007:21976.
  • 8Madsen-Bouterse SA,Mohammad G,Kanwar M,et al.Role of mi-tochondrial DNA damage in the development of diabetic retinopathy,and the metabolic memory phenomenon associated with its progression.Antioxid Redox Signal,2010,[Epub abead of print] .
  • 9Genuth S,Sun W,Cleary P,et al.Glycation and carboxymethyll-ysine levels in skin collagen predict the risk of future 10-year progression of diabetic retinopathy and nephropathy in the diabetes control and complications trial and epidemiology of diabetes interventions and complications participants with type 1 diabetes.Diabetes,2005,54:3103-3111.
  • 10Kowluru RA.Chan PS.Metabolic memory in diabetes-from in vitro oddity to in vim problem;Role of apoptosis.Brain Res Bull,2010,81:297-302.

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