康莱特注射液联合放疗治疗50例骨转移癌的疗效分析

Therapeutic effect of osseous metastatic cancers with Kanglaite injection combined with radiotherapy:report of 50 cases

目的:观察康莱特注射液联合放疗对骨转移癌疼痛的临床疗效。方法:100例骨转移癌患者随机分为观察组(n=50)与对照组(n=50),两组均采用局部放疗30Gy/10F,观察组同时采用康莱特注射液200 ml/d静脉滴入,连用20d,观察两组治疗前后骨痛评分及生活质量评价。结果:观察组病灶部位疼痛明显减轻(P<0.05),患者生活质量评价优于对照组(P<0.05)。结论:康莱特注射液联合放疗对骨转移癌的疗效优于单纯放疗。

Objective：To examine the effects of Kanglaite injection combined with radiotherapy for elieving pain due to metastatic bone tumors. Methods ： Total of patients with metastatic bone tumors were randomized into the observation group （ n = 50 ） and the control group （ n = 50 ）. All of these patients were treated with radiotherapy （ DT 30Gy/10F）. The patients in the observation group were given additional medication consisting of Kanglaite （200ml, i. v. d1-20 ）. Results： The effective rates in the observation group and the control group were significantly different （ P 〈 0.05）. Compared to patients in the control group, patients in the observation group showed a significant increase in the QOL （ P 〈 0.05 ） and a lower hematological toxicity after chemotherapy （ P 〈 0.05 ）. Conclusion： Kanglaite combined with radiotherapy is effective for pain caused by metastatic bone tumors with mild side effects.