过氧化氢氧化合成对叔丁基苯甲酸的研究

STUDY ON THE OXIDATIVE SYNTHESIS OF p-TERT-BUTYLBENZOIC ACID WITH HYDROGEN PEROXIDE

研究了以过氧化氢为氧化剂,液相氧化对叔丁基甲苯(PTBT)合成对叔丁基苯甲酸(PTBA)的反应,考察了各因素对反应的影响。结果表明,适宜的反应条件为:以醋酸钴(Co(AC)2)为催化剂、催化剂与PTBT的摩尔比0.0554、促进剂用量0.04mol、溶剂与PTBT摩尔比9.78、乙酸酐用量0.10mol、反应温度80℃、反应时间7h,在该反应条件下,PTBT转化率为97.66%,PTBA收率为89.20%。

Liquid-phase oxidation of p-tert-butyltoluene （PTBT）using hydrogen peroxide as oxidant to prepare p-tert-butylbenzoic acid（PTBA）was conducted, various factors affected the reaction were studied and optimum reaction conditions were obtained. Under the conditions of using Co（AC）2 as catalyst with a catalyst to PTBT molar ratio of 0. 055 4, using NaBr as oxidative promoter with a dosage of 0.04 mol,a solvent to PTBT molar ratio of 9.78,an acetic anhydride dosage of 0. 10 mol,a reaction temperature of 80 C and a reaction time of 7 h,the conversion of PTBT and the yield of PTBA were 97.66% and 89. 20% ,respectively.