藏药溶脂胶囊干预超重和肥胖症患者33例临床观察

Clinical Observation on 33 Obesity and Overweight Patients Intervented by Tibetan Medicine Rongzhi Capsule

目的观察藏药溶脂胶囊干预超重和肥胖症患者的有效性及安全性。方法33例受试者每次服用溶脂胶囊4粒(每粒0.41g),每日2次,连续服用12周,观察干预前后其体脂参数、证候学积分、血脂等主要指标的变化,进行自身前后对照分析。结果干预后体脂参数、证候学总积分均降低(P<0.05或P<0.01),体重临床控制总有效率为54.54%;证候学积分有效率63.64%;干预后血脂明显降低(P<0.05或P<0.01)。试验中未发生与药物相关的严重不良事件。结论藏药溶脂胶囊对超重和肥胖症患者有较好的临床疗效。

Objective To evaluate the effect and safety of Tibetan Medicine Rongzhi Capsule （Capsule for Dissolving the fat） on obesity and overweight patients. Methods The 33 patients took 4 Rongzhi capsules （0. 41g/capsule） each time, twice a day, 12 weeks in succession. The body fat parameter, symptom scores and blood fat was observed for the self comparative analysis before and after treatment. Results After intervention, the body fat parameter and symptom scores were decreased （P〈0.05 or P〈0.01）. Total effective rate of body weight control was 54.54% the effective rate of symptom score was 63.64%, and the blood fat reduced obviously （P〈0.05 or P〈0.01）. There was no untoward effect relating to Rongzhi Capsule in the experiment. Conclusion Tibetan Medicine Rongzhi Capsule is effective for obesity and overweight patients.