碳酸利多卡因在硬膜外麻醉中的临床应用

The clinical application of Lidocaine Creosote in epidural anesthesia

目的:比较碳酸利多卡因和盐酸利多卡因在硬膜外阻滞中的临床效果。方法:74例腹部或下肢择期手术的患者,ASAⅡ～Ⅲ级。随机分为观察组(碳酸利多卡因组,37例)和对照组(盐酸利多卡因组,37例)。比较两种局麻药的起效时间、阻滞完全时间、麻醉持续时间、阻滞节段、局麻药首剂总量及首剂量维持时间。结果:碳酸利多卡因起效时间、阻滞完全时间均短,与对照组比较,P<0.05;局麻药首剂总量、首剂量维持时间、麻醉持续时间、阻滞节段与对照组比较,P>0.05。结论:碳酸利多卡因应用于硬膜外麻醉,具有阻滞作用强、诱导时间短等优点。

Objeetive： To compare the clinical efficacy of Lidoeaine Hydrochloride and Lidoeaine Creosote in the epidural anesthesia. Methods： 74 eases of patients with selected time operation of abdomen or lower limbs, ASA Ⅱ - Ⅲ. All patients were randomly divided into observation group（Lidocaine Creosote group,37 eases） and control group（Lidoeaine Hydrochloride group,37 cases）.Then compared the onset time, completion time, lasting time, block range, first total volume of novocaine and its lasting time of two kinds of novocaine. Results： Both the onset time and the completion time of observation group were shorter than those of control group, P〈0.05 ;there was no significant difference between the other indexes of two groups, P〉0.05. Conclusion： The application of Lidocaine Creosote in epidural anesthesia has the advantage of strong block effect and short induced time.