心理干预对慢性乙型肝炎患者治疗效果的影响研究

Effect of psychological intervention on patients with chronic type B hepatitis

目的:探讨心理干预对慢性乙型肝炎患者抗病毒治疗期间肝功能及病情的影响。方法:心理干预组59例,在常规抗病毒药物治疗的基础上进行心理干预,对照组49例单纯进行常规抗病毒药物治疗,在干预前、后分别检测肝功能及乙肝表面抗原(HBsAg),比较两次检测的结果,以观察心理干预在抗病毒治疗期间的作用。结果:心理干预前两组患者肝功能、HBsAg无差别,干预后两组患者ALT、AST、ALB、HBsAg转阴率差异有统计学意义(P<0.05)。结论:在常规药物治疗基础上配合心理干预,可以有效改善慢性乙型肝炎患者的肝功能和病情。

Objective To study the effect of psychological intervention on chronic hepatitis B patients＇ liver function and pathogenetic condition. Method The intervention group （n =59） accepted psychological intervention plus medication, while the control group （ n = 49） accepted only routine medication. Each group was tested liver functions and hepatitis B virus surface antigen （HBsAg） before and after intervention, and then found out the effect of psychological intervention by comparing the test results. Results There were no significant differences between tile two groups in liver function and HBsAg before psychological intervention. While after intervention, the two groups showed significant differences in ALT, AST, ALB and HBsAg （ P 〈 0.05 ）. Conclusion It＇s effective to improve chronic hepatitis B sufferers＇liver function and HBsAg by routine medication plus psychological intervention.