奥斯生诺的合成工艺研究

Research on synthesis of osthenol

采取5种去甲基方法,通过去甲基化反应将蛇床子素合成为奥斯生诺,并从中筛选出最佳的方法,收率68%。

Osthenol is a derivate of osthol with effective pharmaco-therapeutical activities. In this article, five demethylation routes were adopted to produce osthenol and a best synthesis route was found to give a product yield of about 68 % .