葱子化学成分的研究

Study on chemical constituents of Semen Allii Fistulosi

目的:研究百合科葱属植物葱Allium fistulosum L.的干燥成熟种子的化学成分。方法:采用大孔树脂柱色谱、硅胶柱色谱、凝胶柱色谱和反相硅胶柱色谱进行分离纯化,通过理化常数和1H-NMR、13C-NMR、ESI-MS等波谱技术进行化合物的结构鉴定。结果:从葱子水提取物的50%乙醇大孔树脂洗脱部位中分离得到了7个化合物,分别鉴定为腺苷(Ⅰ),2,3,4,5,6-五羟基己酸(Ⅱ),1,4-二羟基-2-甲氧基苯(Ⅲ),S-顺式-烯丙基-L-半胱氨酸(Ⅳ),S-反式-烯丙基-L-半胱氨酸(Ⅴ),反-异扁柏脂素(Ⅵ),β-谷甾醇(Ⅶ)。结论:以上化合物均为首次从葱子中分离得到,其中化合物Ⅵ为首次从葱属植物中分离得到。

Objective ： To study the chemical constituents of Semen Allii Fistulosi. Methods ： Isolation and purification were carried out by macroporous absorption resin, silica gel, Sephadex LH-20 and RP-silica. The compounds of Semem Allii Fistulosi were identified and elucidated by spectral and chemical methods. Results：Seven compounds were obtained from water extract of Semen Allii Fistulosi and their structures were determined as adenosine （ Ⅰ ）, 2,3,4,5,6 - pentahydroxyhexanoic acid （ Ⅱ ）, 2-methoxyhydroquinone （ Ⅲ ）, S-（ cis-l-propenyl）-L-cysteine （ Ⅳ ）, S-（trans-l-propenyl） -L-cysteine （ Ⅴ ）, trans-hinokiresinol （ Ⅵ ）, and β-sitosterol （Ⅶ）. Conclusion ： All the compounds are found in Semen Allii Fistulosi for the first time, and compound Ⅵ is found in Allium for the first time.