465例胃癌临床分析

CLINICAL ANALYSIS OF 465 PATIENTS WITH GASTRIC CANCER

目的：探讨胃癌临床病理特点。方法：回顾性分析465例胃癌的性别、年龄、职业、胃镜表现、组织病理特点、临床症状和体征。结果：465例胃癌中男女比例为2．275，以51-60岁年龄段，农民发病率高，症状以上腹痛（占83．92％），黑粪（占95．50％）常见。内镜下3厘米以上，隆起型病灶多见，好发于贲门部，低分化腺癌最常见（占52．47％），直径大于3厘米病灶侵及浆膜层及淋巴结转移率高。胃癌最常转移到肝脏。结论：50岁以上的男性、农民、有消化道症状者应及时做胃镜检查，并特别注意观察大于3厘米的贲门部病灶。

Objective ：To investigate the clinical characteristic of gastric cancer.Methods ：The gender,age,occupation,gastroscopic, histopathologic appearance as well as symptoms and signs were analysed retrospectively. Results： The gastric cancer occurred mostly in male peasants during 51 to 60 years of age.Upper gastric pain and melena presented frequently;protrude type lesions larger than 3cm were frequently localized in cardiac parts under gastroscope; poorly differentiated adenocarcinoma accounted for 47.58%;lesions larger than 3cm possessed higher probability of invading to placenta percreta and metastasis to lymph nodes;liver was the most common organ of metastasis by gastric cancer. Conclusion：Gastroendoscopy is necessary to male peasants older than 50 years with gastroenterologic symptoms;in addition, more attention should be paid to the lesions larger than 3cm in size in cardiac parts.