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蒙特卡罗药动/药效学模型在优化抗菌药物给药方案中的应用 被引量:6

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摘要 在细菌耐药性日益增加的今天,临床治疗中如何恰当选择抗菌药物是临床医生面临的难题。有时根据体外药物敏感性试验选择药物,不一定能获得理想的效果。
作者 叶龙强 蔡挺
出处 《现代实用医学》 2009年第1期5-6,30,共3页 Modern Practical Medicine
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同被引文献51

  • 1赵彩芸,李家泰,张莉,张朴,刘燕.单次静脉美罗培南在健康人体的药代动力学[J].中国临床药理学杂志,2004,20(3):189-192. 被引量:25
  • 2焦正,蒋新国,钟明康,陆伟跃.药物临床研究的计算机模拟[J].中国新药与临床杂志,2005,24(6):491-496. 被引量:13
  • 3史军.药物动力学和药效动力学在抗菌药物新药开发和临床治疗上的应用[J].中国临床药理学与治疗学,2007,12(2):121-133. 被引量:33
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  • 7European Committee for Antimicrobial Susceptibility Testing (EUCAST) of the European Society of Clinical Microbiology and Infection Disease (ESCMID). Determination of antimicrobial susceptibility test breakpoints Infect, 2000, 6: 570-572. Microbiol.
  • 8Gin A, Dilay L, Karlowsky JA, et al. Piperacillin-tazobactam: a beta - lactam/beta-lactamase inhibitor combination [ J ]. Expert Rev Antiinfect Ther, 2007, 5 (3) : 365-383.
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