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空腹高血糖的2型糖尿病患者加用甘精胰岛素或中性鱼精蛋白锌胰岛素的比较 被引量：1

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摘要 目的比较甘精胰岛素和中性鱼精蛋白锌胰岛素对治疗空腹高血糖的2型糖尿病(T2DM)的效果。方法将口服降糖尿病药物治疗无效的48例空腹高血糖的T2DM患者分成2组。患者在保持原口服药物方案不变的基础上,加用甘精胰岛素(16例)或中性鱼精蛋白锌胰岛素(NPH,32例),至空腹指尖血糖<6.0mmol/L。并于治疗第12周对患者进行动态血糖监测。结果两组治疗后空腹血糖(FPG)和糖化血红蛋白(HbA1c)均较治疗前明显下降(<0.05),但两组下降幅度比较差异无统计学意义。在FPG控制良好并相近情况下,甘精胰岛素组全天血糖曲线波动小,夜间低血糖发生率低。结论甘精胰岛素对于稳定全天血糖水平和减少低血糖发生优于NPH,是更为理想的胰岛素基础替代治疗。
作者 曾志红 周晓明 翁利红
机构地区 浙江省龙泉市人民医院
出处 《现代实用医学》 2009年第1期63-63,67,共2页 Modern Practical Medicine
关键词 糖尿病 非胰岛素依赖型 甘精胰岛素 中性鱼精蛋白锌胰岛素
分类号 R587.1 [医药卫生—内分泌]
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共引文献201

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现代实用医学
2009年 第1期

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