舒利迭(50/500)对稳定期中重度COPD患者疗效观察

The efficacy of seretide (50/500) in patients with stable moderate and severe chronic obstructive pulmonary disease

目的观察舒利迭(50/500)对稳定期中重度慢性阻塞性肺疾病(COPD)的疗效。方法将80例经住院治疗处于稳定期中重度COPD患者,随机分为治疗组和对照组。对照组给予常规治疗,治疗组在此基础上给予吸入舒利迭(50/500)。记录治疗前和治疗后的肺功能和血气分析等指标。结果治疗组的总有效率显著高于对照组,两组疗效比较差异有显著性(P<0.01),吸入舒利迭无明显的毒副作用。结论应用舒利迭(50/500)治疗稳定期中重度COPD,能显著改善动脉血气指标,使用安全,值得在临床上推广。

Objective To investigate the effects of treatment using seretide on patients with stable moderate and sever chronic obstructive pulmonary disease. Methods 80 patients with stable moderate and severe COPD after hospital discharge were randomly divided into treatment and control groups. The control group was given conventional treatment, the treatment group was given seretide （50/500） on the basis of conventional treatment. The parameters of lung funetion test and arterial blood gases were measured before and after treatment. Results The efficient of the treatment group significantly higher than that of the control group. Efficacy difference between the two groups was significant （ P 〈 0. 01 ） ; Seretide had no obvious side effects. Conclusion Application of seretide （50/500） in the treatment of stability during the severe COPD clinical can significantly improve blood gas indicators. The use is safe. It is worth promoting in the clinic.