酚妥拉明联合垂体后叶素治疗肺结核咯血临床观察

Clinical observation of phentolamine and pituitary to treat hemoptysis tuberculosis

目的探讨酚妥拉明与垂体后叶素联合治疗肺结核咯血的效果。方法选择我院收治的80例肺结核咯血患者,随机分为治疗组和对照组,治疗组采用酚妥拉明和垂体后叶素联合治疗,对照组采用垂体后叶素治疗,观察两组的治疗效果、咯血停止的时间及副作用。结果治疗组显效率和总有效率分别为62.5%和90%,高于对照组的40%和70%,差异有统计学意义(P<0.05);治疗组咯血停止时间为(1.12±0.51)d,对照组为(2.57±0.60)d,差异有统计学意义(P<0.05);治疗组副作用发生率为5%,对照组发生率为35%,高于治疗组,差异有统计学意义(P<0.05)。结论酚妥拉明与垂体后叶素联用,既能协同止血、减少咯血时间而提高疗效,而且副作用较少,值得临床推广使用。

Objective To explore the effect of phentolamine and pituitary to treat hemoptysis tuberculosis. Methods Select 80 patients and divided into treat group and control group, the treat group were treated with phentolamine and pituitary, while the control group were treated with pituitary, compared the treat effect, the hemoptysis stopped time and aside effects. Results The effect rate and the total effect rate of the treat group were 62.5% and 90%, which were higher than that of the control group, the difference was statistical significant （P 〈 0. 05 ） ; the hemoptysis stopped time of the treat group was （1.12 ± 0. 51 ） d, which of the control group was （2.57 ± 0. 60 ） d, the difference was statistical significant （ P 〈 0.05 ） ; the side effect rate of the treat group was 5 %, which of the control group was 35 %, the difference was statistical significant （ P 〈 0. 05 ）. Conclusion Using phentolamine and pituitary together can reduce the hemoptysis time to improve treat effect, and the side effects is little, it can be widely used in clinic.