期刊文献+

联合他克莫司软膏治愈颜面慢性盘状红斑狼疮一例 被引量:1

原文传递
导出
摘要 患者女,54岁,因鼻部鳞屑性红斑9年余就诊。患者9年前无明显诱因鼻尖部出现一个绿豆大小的鳞屑性红斑,微痒,日晒后加重,逐渐扩大,躯干四肢未见类似皮疹。4年前皮疹扩大至鸡蛋大小,剥离表面鳞屑可见浅表性凹陷(图1),且左侧耳垂、双上肢出现类似皮损,在当地医院就诊,先后以脂溢性皮炎、盘状红斑狼疮、酒渣鼻给予醋酸氟轻松软膏、硫磺软膏等治疗,双上肢皮损消失,但鼻部和左侧耳部皮疹未见明显消退。患者发病以来无发热、乏力、关节痛等不适,无口腔溃疡。既往史无特殊,家族中无类似病史。体检:鼻尖、鼻翼部可见约3cm×3cm大小的红色斑片,形状欠规则,边界清楚,轻度萎缩,表面覆白色鳞屑伴毛细血管扩张。左侧耳垂部可见一约黄豆大小的鳞屑性斑疹,鳞屑难以剥离。
出处 《中华皮肤科杂志》 CAS CSCD 北大核心 2009年第2期90-90,共1页 Chinese Journal of Dermatology
  • 相关文献

参考文献3

二级参考文献32

  • 1Nghiem P,Pearson G,Langley RG.Tacrolimus and pimecrolimus:from clever prokaryotes to inhibiting calcineurin and treating atopic dermatitis.J Am Acad Dermaol,2002,46:228-241.
  • 2Won CH,Seo PG,Park YM,et al.A multicenter trial of the efficacy and safety of 0.03% tacrolimus ointment for atopic dermatitis in Korea.J Dermatolog Treat,2004,15:30-34.
  • 3Paller AS,Lebwohl M,Fleischer AB Jr,et al.Tacrolimus ointment is more effective than pimecrolimus cream with a similar safety profile in the treatment of atopic dermatitis:results from 3 randomized,comparative studies.J Am Acad Dermatol,2005,52:810-822.
  • 4Lebwohl M,Freeman AK,Chapman MS,et al.Tacrolimus ointment is effective for facial and intertriginous psoriasis.J Am Acad Dermatol,2004,51:723-730.
  • 5Rozycki TW,Rogers RS 3rd,Pittelkow MR,et al.Topical tacrolimus in the treatment of symptomatic oral lichen planus:a series of 13 patients.J Am Acad Dermatol,2002,46:27-34.
  • 6Kaliakatsou F,Hodgson TA,Lewsey JD,et al.Management of recalcitrant ulcerative oral lichen planus with topical tacrolimus.J Am Acad Dermatol,2002,46:35-41.
  • 7Thomson MA,Hamburger J,Stewart DG,et al.Treatment of erosive oral lichen planus with topical tacrolimus.J Dermatolog Treat,2004,15:308-314.
  • 8Lyon CC,Smith A J,Beck MH,et al.Parastomal pyoderma gangrenosum:clinical features and management.J Am Acad Dermatol,.2000,42:992-1002.
  • 9Petering H,Kiehl P,Breuer C,et al.Pyoderma gangrenosum:successful topical therapy with tacrolimus (FK506).Hautarzt,2001,52:47.
  • 10Goldman D.Tacrolimus ointment for the treatment of steroid-induced rosacea:a preliminary report.J Am Acad Dermatol,2001,44:995-998.

共引文献24

同被引文献22

  • 1U Wollina,G Hansel.The use of topical calcineurin inhibitors in lupus erythematosus:an overview.JEADV 2008;22:1-6.
  • 2Panhans-Gross A,Novak N,Kraft S,et al.Human epidermal Langerhans'cells are target for the immunosuppressive macrolide tacrolimus (FK-506).J Allergy Clin Immunol 2001;107:345.
  • 3Stuetz A,Grassberger M,Meingassner JG.Pimecrolimus(Elidel,SDZ ASM981)-preclinical pharmacologic profile and skin selectivity.Semin Cutan Med Surg 2001;20(4):233.
  • 4Boguniewicz M,Leung DY.Pathophysiologic mechanisms in atopic dermatitis.Semin Cutan Med Surg 2001;20(4):217.
  • 5Kreuter A,Gambichler T,Breuckmann F,et al.Pimecrolimus 1% cream for cutaneous lupus erythematosus.J Am Acad Dermatol 2004;51:407-410.
  • 6Kanekura T,Yoshii N,Terasaki K,et al.Efficacy of topical tacrolimus for treating the malar rash of systemic lupus erythematosus.Br J Dermatol 2003;148:353-356.
  • 7Von Pelchrzim R,Schmook T,Friedrich M,et al.Efficacy of topical tacrolimus in the treatment of various cutaneous manifestations of lupus erythematosus.Int J Dermatol 2006;45(1):84-85.
  • 8Bhm M,Gaubitz M,Luger TA,et al.Topical tacrolimus as a therapeutic adjunct in patients with cutaneous lupus erythematosus.Dermatology 2003;207:381-385.
  • 9Cassis TB,Callen JP.Bupropion-induced subacute cutaneous lupus erythematosus.Australas J Dermatol 2005;46:266-269.
  • 10Meller S,Bruch-Gerharz D,Ruzicka T,et al.Topische Behandlung des subakut-kutanen Lupus erythematodes mit Tacrolimus.Hautarzt 2005;56:368-369.

引证文献1

二级引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部