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血管内皮生长因子与子宫内膜癌

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摘要 血管内皮生长因子（vascular endothelial growth factor，VEGF）是一组功能强大且能产生多种效应的细胞因子。它可诱导血管及淋巴管生成，不仅在胚胎发育、创伤愈合中发挥重要作用，而且与肿瘤的生长、浸润和转移关系密切。子宫内膜癌是女性生殖道常见的三大恶性肿瘤之一，占女性生殖道恶性肿瘤的20％-30％，其发病率持续上升，且发病年龄有降低趋势。近年的研究表明，VEGF可能在子宫内膜癌的发生、发展、转移以及预后方面发挥重要作用。
作者 纪宝凤 毛用敏
机构地区 天津市蓟县妇幼保健院 天津市心血管病研究所
出处 《天津医药》 CAS 北大核心 2009年第2期152-155,共4页 Tianjin Medical Journal
关键词 血管内皮生长因子类 子宫内膜肿瘤 淋巴管生成 癌
分类号 R735.2 [医药卫生—肿瘤] R737.33 [医药卫生—肿瘤]
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参考文献27

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二级参考文献38

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天津医药
2009年 第2期

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