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MicroRNA基因簇的多样性与进化 被引量：4

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摘要 microRNA(miRNA)基因簇是一类miRNA基因在染色体上成簇排列形成的基因群.在动植物基因组中,已发现存在大量簇生排列的miRNA基因.然而这种簇生排列方式所具有的功能意义尚不完全清楚.miRNA基因簇常位于一个多顺反子内,通过共表达在胚胎发育、细胞周期和细胞分化等诸多方面发挥协同调控的功能.基于近些年来的研究进展,本文综述了miRNA基因簇在动物染色体上分布的多样性,表达与功能的协同性,以及重复和转座介导下miRNA基因簇产生与消亡的适应性进化过程.
作者 张雁峰 张锐 宿兵
机构地区 中国科学院昆明动物研究所
出处 《中国科学（C辑）》 CSCD 北大核心 2009年第1期114-120,共7页 Science in China(Series C)
基金 国家自然科学基金重点项目(批准号:306300130)资助
关键词 miRNA基因簇 基因重复 适应性进化 转座
分类号 Q3 [生物学—遗传学]
  • 相关文献

参考文献54

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共引文献9

同被引文献40

  • 1段成国,王春晗,郭惠珊.microRNA对植物生长发育和病毒侵染的调控[J].科学通报,2006,51(4):369-377. 被引量：4
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引证文献4

二级引证文献23

中国科学（C辑）
2009年 第1期

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