3Unger RH ,Grundy S. Hyperglycaemia as an inducer as well as a consequence of impaired islet cell funtion and insulin resistance: implications for the management of diabetes[J]. Diabetologia, 1985,28(3) : 119-121.
4Tosehi E, Camastra S, Sironi AM, et al. Effect of acute hyperglycemia on insulin secretion in humans [J]. Diabetes, 2002,51(Suppl 1) :S130-133.
5Hsieh CH, Hung YJ, He CT, et al. The capability of glucose toxicity on severe type 2 diabetes[J]. Endocr Res, 2005,31 (2):149-158.
4PURRELLO F, RABUAZZA A M. Metabolic factors that affect beta-cell function and survival[J]. Diabet Nurt Metab,2000,13(2):84-91.
5SIVITZ W I. Lipotoxicity and glucotoxicity in type 2 diabetes.Effects on development and progression[J]. Postgrad Med,2001,109(4) : 55-59,63-64.
6DEL PRATO S,MARCHETTI P,BONADONNA R C. Phasic insulin releasa and metabolic regulation in type 2 diabetes[J].Diabetes Care,2002,51(suppl 1) :s109-116.
7ROBERTSON R P, HARMON j, TRON P O, a al. Glucose toxicity in β-cells: type 2 diabetes, good radicals gone bad, and the glutathione connection[J]. Diabetes Care, 2003, 52 (3) :571-587.
8MAEDLER K, SEERGEEV P, RIS F, a al. Glucose-induced β cell production of IL-1βcontrihutes to glucotoxicity in human pancreatic islets[J]. J Clin Invest, 2002,110 (6) : 851-860.
9LENHARD M J, REEVES G D. Continouus subcutaneous insulin infusionz a comprehensive review of insulin pump therapy[J]. Arch Intern Med,2001,161(19) : 2293-2300.
10DUPUY O, MAYAUDON H, PALOU M,et al. Optimized transient insulin infusion in uncontrolled type 2 diabetes:evaluation of a pragmatic attitude[J]. Diabet Med, 2000, 26(5) :371-375.