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空肠弯曲菌耐药机制研究进展 被引量：4

Advance in Mechanism of Antibiotic Resistance in Campylobacter jejuni
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摘要 空肠弯曲菌是一种全球关注的人兽共患病病原菌,由于滥用抗生素而造成其耐药性不断增强,成为公共卫生日益关注的问题。各类抗生素作用位点的基因突变是诱发空肠弯曲菌对各类临床常用的抗生素产生耐药的主要原因,同时细菌对药物的外排机制也在其对抗生素耐药过程中发挥了一定的作用。文章对空肠弯曲菌对各类临床常用抗生素的耐药机制做一综述。 Campylobacter jejuni is a zoonotic pathogen of global concern. Due to the abuse of antibiotics, antibiotic resistance to Campylobacter jejuni is increasing and becoming a serious public health problem. The gene mutation of antibiotic target sites is the major reason of antibiotic resistance in Campylobacter jejuni. Moreover, alternation of drug efflux mechanism plays an important role in formation of antibiotic resistance. This paper reviewed the mechanims of resistance to commonly used antibiotics in Campylobacter jejuni.
作者 海泉 张焕容 杨发龙 岳华
机构地区 西南民族大学生命科学与技术学院
出处 《动物医学进展》 CSCD 北大核心 2009年第2期61-64,共4页 Progress In Veterinary Medicine
基金 国家菌种平台资源项目(2005DKA21205-11) 西南民族大学博士基金项目
关键词 空肠弯曲菌 耐药机制 基因突变 药物外排 Carnpylobacter j ej uni mechanism of resistance gene mutations drug efflux
分类号 S852.613 [农业科学—基础兽医学]
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参考文献20

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共引文献41

同被引文献50

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引证文献4

二级引证文献15

动物医学进展
2009年 第2期

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