有氧运动对抑郁女大学生抑郁状态、单胺递质的影响

Effect of Aerobic Exercise on Depression and Monoamine Transmitters in Female College Students with Depression Symptoms

目的探讨有氧运动对于抑郁女大学生抑郁状态、单胺递质和体质状况的影响。方法将30名轻度到中度抑郁的女大学生分为两组:抑郁运动组15名(进行8周,每周5次,每次50 min,强度为70%-80%最大心率的健身跑)和抑郁对照组15名。另外选取15名正常无抑郁的女大学生为正常对照组。分别于实验前后测量受试者的抑郁状态,5-HT、NE、皮质醇水平,体成分和最大摄氧量。结果8周有氧运动后,抑郁运动组的CES-D量表评分下降,抑郁症状减轻。抑郁患者血浆5-HT、NE水平下降,皮质醇水平升高。经过8周有氧运动后,抑郁患者血浆5-HT、NE水平上升,皮质醇水平下降;体重、体脂百分比、心率下降,瘦体重、最大摄氧量升高。结论抑郁可能与5-HT、NE的下降,皮质醇的升高有关。8周的有氧运动可以有效地增进抑郁患者的身体机能和心理健康。

Objective： To investigate the effect of aerobic exercise on depressive state, the levels of monoamine transmitters and physiological fitness variables in female college students with depression symptoms. Methods： Thirty female volunteers with mild- to - moderate depressive symptoms were assigned to an exercise group of depression and control group of depression. Fifteen health female volunteers were assigned to a normal control group. The exercise group must do the aerobic exercise regimen for 8 weeks, which consisted of five 50 - rain sessions per week of a group jogging training at 70% - 80% HRmax intensity. The variables measured were CES- D rating scale, 5 - HT, NE and eortisol levels, body composition and peak oxygen uptake before an after the test. Result： After 8 Weeks exercise the CES - D total depressive score showed a significant decrease in the exercise group. The training group had a significantly reduced cortisol level, weight, body fat percentage, resting heart rate and increased 5 - HT level, NE level, lean body mass and peak oxygen uptake. Conclusion： Depression may be relate to the decrease of the content of monoamine transmitters and the increase of cortisol. 8 weeks aerobic exercise can improve physiological fitness and mental health in female college students with depression symptoms.