罗哌卡因与布比卡因用于颈丛阻滞的比较

Comparison Between Ropivacaine and Bupivacaine in Block Anesthesia of Cervical Plexus

目的观察罗哌卡因与布比卡因用于颈丛阻滞的特性及安全性,评价罗哌卡因的临床效果。方法60例择期手术病人,随机分为罗哌卡因组(30例)与布比卡因组(30例),观察两组镇痛效果、起效时间、镇痛持续时间及不良反应。结果两组药物镇痛效果、起效时间差异无统计学意义。罗哌卡因组的镇痛持续时间短于布比卡因组(P<0.05)。循环系统并发症少于布比卡因组(P<0.05)。结论低浓度罗哌卡因用于颈丛阻滞与等剂量布比卡因相比镇痛效应相当,并发症少且恢复快,是安全、可行的。

Objective To observe the feature and the safety of ropivacaine and bupivacaine in block anesthesia of cervical plexus, and to appraise the clinical outcome of ropivacaine. Methods Sixty patients who would undergo selective operation were randomized into ropivacaine group and bupivacaine group. Observation was carried out on the aspects of analgetic effect, beginning time, persisting duration and adverse reaction. Results There were no statistical differences in analgetic effect and beginning time between the two groups. The analgetic persisting duration was shorter in the ropivacame group than in the bupivacaine group （ P 〈 0.05）, but the complications of circulatory system were fewer in the former group （ P 〈 0.05）. Conclusion The analgetic effect of ropivacaine is equal to that of bupivacaine when it is applied to block anesthesia of cervical plexus. Besides, it is safe because of fewer complications.