衣原体性非淋菌性尿道炎混合感染和临床治疗的实验研究

MIXED INFECTION AND CLINICAL THERAPY IN NONGONOCOCCAL URETHRITIS CAUSED BY C. TRACHOMATIS

该文报道,用快速免疫法、PCR 和培养法对214例 Ct 阳性 NGU 患者进行了混合感染和临床治疗研究。结果显示:男女合并统计 Ct+Uu,Ct+Mh,Ct+Gc,Ct+Tv,Ct+Uu+Mh,Ct+Uu+Cd,C1+Uu+Tv 混合感染率分别为61(28.50%),34(15.88%),16(7.47%),14(6.54%),21(9.81%),8(3.73%),11(5.14%),两者之间无显著性差异(x^2=0.014,0.79,1.64,0.10,3.38,0.41,0.44,P>0.05)。女性患者 Ct+Cd 12例(20.68%)明显高于男性患者Ct+Cd 11例(7.05%),两者之间有显著性差异(x^2=6.27,P<0.01)。在103例男性 NGU 患者,阿奇红霉素组与美满霉素组疗效相似,两者比较,无显著性差异(P>0.05)。该研究结果为 Ct 阳性 NGU 混合感染病因学诊断、治疗和预防提供了实验依据。

Research on mixed infection, as well as clinical therapy were carried out in 214 patients with nongonococcal urethritis (NGU) caused by C. trachomatis using clearview chlamydia, PCR and cultivation methods. The results show that the mixed infective rates of Ct + Uu, Ct + Mh, Ct + Gc, Ct+Tv, Ct+Uu+Mh, Ct + Uu + Cd, and Ct + Uu+Tv, are 61(28. 50%), 34(15.88%), 16(7.47%), 14(6. 54%), 21(9.81%), 8(3.73%), and 11(5.14%), respectively, with no obvious difference between the sexes (P>0.05). Ct+Cd is thought to be linked to gender, because it was found more often in women than in men (P<0.01). Of the 103 cases of NGU in men, az-itromycin was as effective as minocycline, with no significant difference (P>0. 05). The results in these studies can provide experimental basis for the diagnosis, treatment, and prevention of mixed infective etiology in NGU caused by C. trachomatis.