多层螺旋CT肝脏灌注成像技术在华支睾吸虫所致不同程度肝硬化中的应用

Multi-Slice Spiral CT Perfusion Imaging Technique in Application of Extent of Liver Cirrhosis Caused by Clonorchiasis

目的探讨多层螺旋CT灌注成像技术评价华支睾吸虫所致不同程度肝硬化的肝血流动力学变化的可行性及其价值。方法分别对肝硬化组28例(轻度14例、中度9例、重度5例)和正常组10例进行肝脏CT灌注扫描,研究其CT灌注参数值的差异性。结果不同程度肝硬化的血流量(BF)、血容量(BV)、肝动脉分数(HAF)、门静脉灌流量(PVP)值间有显著统计学差异;轻度肝硬化与正常肝CT灌注参数值(BV、BF、HAF、PVP)间无明显统计学差异;中、重度肝硬化与正常肝CT灌注参数值(BV、BF、HAF、PVP)间均有明显统计学差异。结论CT灌注参数值与肝硬化的严重程度相关,可作为评价肝硬化程度的重要指标。

Objective To investigate the feasibility and value of multi-slice spiral CT perfusion imaging technique in assessment of the extent of liver cirrhosis caused by clonorchiasis. Methods 28 cases of liver cirrhosis group （14 cases of mild, 9 cases of moderate, 5 cases of severe） and 10 cases of normal liver perfusion CT scan, to study the difference ofCT perfusion parameters. Results The extent of liver cirrhosis of different blood flow （BF）, blood volume （BV）, hepatic arterial fraction （HAF）, portal vein perfusion flow （PVP） valued a significant statistical difference; mild liver cirrhosis and normal liver CT perfusion parameters value （BV, BF, HAF, PVP） was no significant statistical difference; moderate and severe cirrhosis and normal liver CT perfusion parameters （BV, BF, HAF, PVP） showed significant difference between. Conclusion CT perfusion parameters related to the liver cirrhosis, which can be used as an important indicator for assessment of the extent of liver cirrhosis.