药物中间体对氟苄胺的合成

目的:合成药物中间体对氟苄胺。方法:以对硝基苯甲酸为原料经氟化、酰化、还原3步合成了药物中间体对氟苄胺。结果:总收率达30.43%。结论:本法具有原料易得、成本低廉、操作安全、工艺简单等特点。

Objection：To synthesize ethyl p-Fluorobenzylamine.Methods：p-Fluorobenzylamine which was the intermediate compound of some medicine was synthesized by 3 steps fluorzation,acylation and reduction with p-Nitrobenzoic acid as starting material.Resuhs：The overall yield was 30.43%.Conclusion：This method was simple and safe.The raw material was abundant the cost was low.