加深认识 提高多发性硬化诊治水平

The more understanding,the more facility to diagnosis and therapy of multiple sclerosis

多发性硬化(MS)的诊断核心始终围绕着疾病的时间多发与空间多发性。虽然当前确定的一些MS诊断标准已被广泛接受,但是没有一种疾病的出现与发展会按诊断标准的内容要求而罗列在临床医生案前。MS的诊断仍然是基于临床的一个综合性判断与排它性诊断。循证医学证据表明几种修饰药物治疗MS具有一定效果。MS完整的治疗方案仍应结合临床分型、活动度、分期等制定,治疗的范围包括控制急性发作、预防复发与进展、处理症状及康复神经功能四方面,而且考虑到医疗制度、经济水平和外界因素的影响,治疗需个体化。

The diagnostic core of multiple sclerosis（MS） always requires dissemination in space and time since the publication of the first criteria over 40 years ago. Though several modified clinical eriterias have been proposed to diagnosis MS, no paitents must meet such condition in diagnostic criteria because of the reticular clinical manifestation of this disease. The diagnosis of MS is still based on elinieal parameters including detailed history and a careful examination to exclude alternative disease. The effects of some disease modifying agents to MS have been confirmed by evidence-based medicine. But the intact treatment plan must contain aspects of acute attacks,prevention of relapses and progression ,management of symptoms, and rehabilitation. The individualized treatment is needed according to the medical insurance, payment ability and other influencing factors in China.