热疗加放射治疗局部晚期宫颈癌

COMBINATION OF HYPERTHERAPY WITH RADIOTHERAPY VERSUS RADIOTHERAPY ALONE FOR LOCALLY ADVANCED CARCINOMA OF THE CERVIX

观察热疗加放射在治疗局部晚期宫颈癌的作用。从１９９４年１月－１９９６年１２月收治局部晚期宫颈癌６０例，分为两组。热放组３０例，外照射平均剂量５０．３Ｇｙ（全盆腔），腔内放疗平均剂量３９．４Ｇｙ／Ａ点，腔内热疗４３℃～４５℃／４０ｍｉｎ～４５ｍｉｎ，每周一次，共４次。单放组３０例，外照射平均剂量４９．５Ｇｙ／全盆腔，腔内放疗平均剂量３６．１３Ｇｙ／Ａ点。肿瘤Ⅲ期完全消退率，热放组和单放组各为８０％和１３．３％，Ｐ＜０．０１。热疗加放疗治疗局部晚期宫颈癌近期疗效好。

To observe the effect of carcioma hypertherapy with radiotherapy in treating the petients with locally advanced cervix cancer, 60 patients with locally advanced carcinoma of the uterine cervix were treated from January 1994 to December 1996. It was divided into two groups: hypertherapy with radiotherapy group (H+Rt), on 30 patients external irradiation average doses of 50.3 Gy (pelvic cavity), intracavitary irradiation average doses of 39.4 Gy (point A), intracavitary hypertherapy 43～45℃/40～45 min, four times weekly and radiotherapy group (Rt only) of 30 patients external irradiaton average doses of 49.5 Gy (pelvic cavity), intracavitary irradiation average doses of 39.4 Gy (point A). The complete response rate (CR) H+Rt and Rt only were 80% and 13.3% respectively (p<0.01). A higher complete respons rate in patients with locally advanced cervix cancer is observed with radiotherapy and combination hypertherapy.